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Generic Name: PROMETHAZINE (proe-METH-a-zeen)

Product Description

This medicine is a phenothiazine used to treat or prevent nausea, vomiting, or motion sickness. It may also be used to treat allergies and other conditions as determined by your doctor.

Medication Name







25 mg

30 Tab.




25 mg

90 Tab.



Prescription Promethazine Drug Information

BEFORE USING THIS MEDICINE: WARNING: THIS MEDICINE MAY CAUSE SEVERE AND SOMETIMES FATAL breathing PROBLEMS in children less than 2 years of age. DO NOT USE THIS MEDICINE in children under 2 years old. USE CAUTION WHEN GIVING THIS MEDICINE TO CHILDREN over 2 years old. Do not give this medicine with any other medicines that can cause breathing problems. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking bromocriptine, pergolide, astemizole, terfenadine, or cisapride.

ADDITIONAL MONITORING OP YOUR DOSE OR CONDITION may be needed if you are taking haloperidol, levodopa, lithium, meperidine, methyldopa, tramadol, barbiturates (such as phenobarbital), MAOI medicines (such as furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, or tranylcypromine), tricyclic antidepressants (such as amitriptyline or nortriptyline), narcotic pain medicines, or certain medicines for high blood pressure (ACE inhibitors such as lisinopril or captopril). You may need to be monitored if you are taking certain other medicines that cause drowsiness. Contact your doctor or pharmacist if you are unsure if you are taking any of these medicines. Inform your doctor of any other medical conditions, including seizures, lung problems (such as COPD), trouble breathing while asleep (apnea), certain types of glaucoma (narrow-angle), prostate problems, certain urinary problems (bladder neck obstruction), heart problems, blood pressure problems, blood problems (including porphyria), liver problems, certain types of stomach problems (pyloroduodenal obstruction), certain types of stomach ulcers (stenosing peptic ulcer), bone marrow problems, allergies, pregnancy, or breast-feeding.

THIS MEDICINE SHOULD NOT BE USED to treat asthma or certain other breathing problems, or in children who have symptoms of Reye's Syndrome. If you are unsure of the symptoms of Reye's Syndrome, ask your doctor or pharmacist. DO NOT USE THIS medicine in patients who are unconscious or are in a coma. Use of this medicine in children under age 2 is not recommended. Discuss with your doctor the risks and benefits of giving this medicine to your child. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine. HOW TO USE THIS MEDICINE: Follow the directions for using this medicine provided by your doctor. THIS MEDICINE MAY BE TAKEN WITH FOOD if it upsets your Stomach. IF YOU ARE USING THIS MEDICINE FOR MOTION SICKNESS: take a dose at least 30 to 60 minutes before you begin traveling. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. CAUTIONS: DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. DO NOT EXCEED THE RECOMMENDED DOSE or take this medicine for longer than prescribed without checking with your doctor. Laboratory and/or medical tests may be performed to monitor your progress or to check for side effects. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking this medicine. This medicine may affect some laboratory tests. Make sure your doctors, nurses, and laboratory technicians know you are using this medicine. Because this medicine may interact with certain diagnostic and anesthetic medicines, BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. THIS MEDICINE MAY CAUSE drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. THIS MEDICINE WILL ADD TO THE EFFECTS of alcohol and other depressants. Do not drink alcohol without first discussing it with your doctor. Ask your pharmacist if you have questions about which medicines are depressants. THIS MEDICINE MAY CAUSE increased sensitivity to the sun. Avoid exposure to the sun or sunlamps until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. DO NOT BECOME OVERHEATED in hot weather or during exercise or other activities since heatstroke may occur. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN CHILDREN OR IN THE ELDERLY because they may be more sensitive to the effects of this medicine. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking this medicine. IF YOU HAVE DIABETES, this medicine may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.

POSSIBLE SIDE EFFECTS: SIDE EFFECTS, that may go away during treatment, include drowsiness, dizziness, dry mouth, blurred or double vision, nausea, or vomiting. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience yellowing of the eyes/skin, unusual or involuntary muscle twitching or movements, or unusual tendency to burn in the sun. CONTACT YOUR DOCTOR IMMEDIATELY if you experience fever; mental or mood changes; fast, slow, or irregular heartbeat; confusion; hallucinations; seizure; unusual sweating; muscle spasms; swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include shortness of breath, trouble breathing, dry mouth, unusual or severe drowsiness or restlessness, severe dizziness, flushing, nightmares, dilated pupils, loss of consciousness, and seizures. ADDITIONAL INFORMATION: DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out. The information in this monograph is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This information is generalized and is not intended as specific medical advice. If you have questions about the medicines you are taking or would like more information, check with your doctor, pharmacist, or nurse.


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